Ethanol → Ethyl 3-bromo-4-methoxyphenylacetate

HRID 38683

反応式

HRID 38683 の反応式
[Br:1][C:2]1[CH:3]=[C:4]([CH2:10][C:11]([OH:13])=[O:12])[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].[CH3:14][CH2:15]O>Cl>[CH2:14]([O:12][C:11](=[O:13])[CH2:10][C:4]1[CH:5]=[CH:6][C:7]([O:8][CH3:9])=[C:2]([Br:1])[CH:3]=1)[CH3:15]

参加物

4

反応物 2

HCID 702EthanolHCID 1366153-Bromo-4-methoxyphenylacetic acid

生成物 1

HCID 57419861Ethyl 3-bromo-4-methoxyphenylacetate

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid触媒

反応条件

温度
80 °C

実験手順

3-Bromo-4-methoxyphenylacetic acid (4.1 g, 16.7 mmol) in EtOH (100 mL) was treated with concentrated HCl (2 drops) and heated to 80° C. for 3 days. After cooling to room temperature, the mixture was concentrated to give the title compound.

後処理

  1. temperatureAfter cooling to room temperature
  2. concentrationthe mixture was concentrated

出典と根拠

ORDレコード
ord-030b5dbf3810429cbd2c12d01eaaf0e3
出典データセット
uspto-grants-2013_09
特許番号
US08524748B2

関連ノート

読み込み中…