Triethylamine → N-[(4-chlorophenyl)methyl]-N',N'-diethylethane-1,2-diamine

HRID 388313

反応式

HRID 388313 の反応式
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH2:7])=[CH:4][CH:3]=1.Br.Br[CH2:12][CH2:13][N:14]([CH2:17][CH3:18])[CH2:15][CH3:16].C(N(CC)CC)C>ClCCl>[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH:7][CH2:12][CH2:13][N:14]([CH2:17][CH3:18])[CH2:15][CH3:16])=[CH:4][CH:3]=1

参加物

5

反応物 3

HCID 8471TriethylamineHCID 660364-ChlorobenzylamineHCID 706072-Bromoethyldiethylammonium bromide

生成物 1

HCID 296048N-[(4-chlorophenyl)methyl]-N',N'-diethylethane-1,2-diamine

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

4-Chlorobenzylamine (1.0 mL, 8.2 mmol) was added to a solution of 2-bromo-N,N-diethylethylamine hydrobromide (2.4 g, 9.0 mmol) and triethylamine (3.4 mL, 25 mmol) in dichloromethane (16 mL). The mixture was stirred at room temperature for 5 hours. The mixture was then concentrated to give N1-(4-chlorobenzyl)-N2,N2-diethylethane-1,2-diamine as an oil which was used immediately without purification.

後処理

  1. concentrationThe mixture was then concentrated

出典と根拠

ORDレコード
ord-e85b75c05cc14e2a8c6011cff52a982c
出典データセット
uspto-grants-2013_02
特許番号
US08377937B2

関連ノート

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