Sodium Chloride → Epinephrine
反応式
[CH3:1][NH:2][CH2:3][C@H:4]([OH:13])[C:5]1[CH:6]=[CH:7][C:8]([OH:12])=[C:9]([OH:11])[CH:10]=1.Cl.[Cl-].[Na+]>O>[CH3:1][NH:2][CH2:3][C@H:4]([OH:13])[C:5]1[CH:6]=[CH:7][C:8]([OH:12])=[C:9]([OH:11])[CH:10]=1参加物
4
実験手順
1.2 g of epinephrine HCl, 10.0 g of polyvinylpyrrolidone K 12 prepared as in Example 7 and 7.5 g of sodium chloride were dissolved in 998.0 g of water for injections which had been boiled and cooled under nitrogen. The solution was sterilized by filtration through a 0.22 μm filter and dispensed under nitrogen into 1 ml ampoules.
後処理
- temperaturecooled under nitrogen
- filtrationThe solution was sterilized by filtration through a 0.22 μm
- filtrationfilter
出典と根拠
- ORDレコード
- ord-a03c66ed758f4aabbd732eea919a75e3
- 出典データセット
- uspto-grants-2013_09
- 特許番号
- US08524827B2
反応ノート
読み込み中…