反応式
[CH:1]1([CH:4]=O)[CH2:3][CH2:2]1.[CH3:6][S:7]([NH2:10])(=[O:9])=[O:8]>C1(C)C=CC=CC=1.CC(C)[O-].[Ti+4].CC(C)[O-].CC(C)[O-].CC(C)[O-]>[CH:1]1([CH:4]=[N:10][S:7]([CH3:6])(=[O:9])=[O:8])[CH2:3][CH2:2]1参加物
5
反応条件
- 温度
- 100 °C
実験手順
To a solution of cyclopropanecarbaldehyde (0.374 mL, 5 mmol) and methanesulfonamide (0.523 g, 5.5 mmol) in toluene (15 mL) was added titanium(IV) isopropoxide (2.93 mL, 10 mmol), and the mixture was heated to 100° C. for 1 day. The mixture was cooled to room temperature and concentrated in vacuo. The residue was placed under high vacuum for 30 min to give a biphasic mixture. The top layer was discarded. The residue was used in next step without further purification.
後処理
- temperatureThe mixture was cooled to room temperature
- concentrationconcentrated in vacuo
- customto give a biphasic mixture
- customThe residue was used in next step without further purification
出典と根拠
- ORDレコード
- ord-897fb256a2e34a17bf3f9cbbdceb3a8a
- 出典データセット
- uspto-grants-2013_02
- 特許番号
- US08383827B2
関連ノート
読み込み中…