Iodoethane → o-Diethoxybenzene

HRID 392169ノート

反応式

HRID 392169 の反応式
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[OH:10])[CH3:2].I[CH2:12][CH3:13].C(=O)([O-])[O-].[K+].[K+].C(OCC)(=O)C>CN(C)C=O>[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[O:10][CH2:12][CH3:13])[CH3:2]

参加物

6

反応物 4

HCID 6340IodoethaneHCID 8857Ethyl AcetateHCID 11430Potassium CarbonateHCID 667552-Ethoxyphenol

生成物 1

HCID 74904o-Diethoxybenzene

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

反応条件

温度
80 °C

実験手順

15.0 g of 2-ethoxyphenol, 18.0 ml of iodoethane and 30.0 g of potassium carbonate were suspended in 150 ml dimethylformamide, and the mixture was stirred at 80° C. for 30 hours. Ethyl acetate was added thereto, and the mixture was washed with water for five times and with brine, and then dried over anhydrous magnesium sulfate. The solvent was evaporated to give the title compound quantitatively as a red-brown oil.

後処理

  1. washthe mixture was washed with water for five times and with brine
  2. dry with materialdried over anhydrous magnesium sulfate
  3. customThe solvent was evaporated

出典と根拠

ORDレコード
ord-2e7a80f7df9d46a8be69355706f5ae2c
出典データセット
uspto-grants-2004_10
特許番号
US06800644B2

反応ノート

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