1-O-alpha-D-Glucopyranosyl-D-mannitol → Trehalose

HRID 393492

反応式

HRID 393492 の反応式
[CH2:1]([OH:23])[C@H:2]1[O:7][C@H:6]([O:8][CH2:9][C@@H:10]([OH:19])[C@@H:11]([OH:18])[C@H:12]([OH:17])[C@H:13]([OH:16])[CH2:14][OH:15])[C@H:5]([OH:20])[C@@H:4]([OH:21])[C@@H:3]1[OH:22]>O>[CH2:1]([OH:23])[C@H:2]1[O:7][C@H:6]([O:8][C@H:9]2[O:16][C@H:13]([CH2:14][OH:15])[C@@H:12]([OH:17])[C@H:11]([OH:18])[C@H:10]2[OH:19])[C@H:5]([OH:20])[C@@H:4]([OH:21])[C@@H:3]1[OH:22]

参加物

3

反応物 1

HCID 887351-O-alpha-D-Glucopyranosyl-D-mannitol

生成物 1

HCID 7427Trehalose

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
125 °C

実験手順

Ninety-five parts by weight of high-purity crystalline trehalose hydrate and 18 parts by weight of palatinit were placed in a dissolving tank, and admixed with and dissolved by heating in 63 parts by weight of water. The solution was placed in a concentrator, concentrated to boil down by heating to 125° C. under reduced pressure, continued concentrating by heating under reduced pressure while keeping the temperature until reaching to a moisture content of about 1.0%. Similarly as in Example A-1, the concentrate was subjected to an extruder for forming, cooled to ambient temperature to obtain a short-rod thermoplastic shaped-body of trehalose, about 2 mm in diameter and about 4 mm in length. Since the product was a colorless, transparent or translucent, and substantially amorphous shaped-body having thermoplasticity and satisfactory storage-stability under indoor circumstances, it can be arbitrarily reheated to a temperature of about 90° C. to about 160° C. to impart it free-flowing ability, then transformed or processed into a shaped-body with an appropriate form with or without using other substances having different functions. The product can be also used arbitrarily for preparing a paste containing trehalose by dissolving in a relatively-small amount of hot water, and the resulting paste can be used intact in an amorphous form or used as a powdered base after crystallization of trehalose.

後処理

  1. dissolutiondissolved
  2. concentrationconcentrated
  3. concentrationcontinued concentrating
  4. temperatureby heating under reduced pressure
  5. customfor forming
  6. temperaturecooled to ambient temperature

出典と根拠

ORDレコード
ord-e2d0f268a5e4473baed019330ac142fc
出典データセット
uspto-grants-2004_10
特許番号
US06808651B1

関連ノート

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