4-Methoxy-3-(2-methoxyethoxy)nitrobenzene → 4-Methoxy-3-(2-methoxyethoxy)aniline
反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]([O-])=O)=[CH:5][C:4]=1[O:12][CH2:13][CH2:14][O:15][CH3:16]>[Pd].C(OCC)(=O)C>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH2:9])=[CH:5][C:4]=1[O:12][CH2:13][CH2:14][O:15][CH3:16]参加物
4
実験手順
A mixture of 4-methoxy-3-(2-methoxyethoxy)nitrobenzene (7 g, 30 mmol) and 10% palladium-on-charcoal catalyst (1.4 g) in ethyl acetate (70 ml) was stirred under hydrogen at 3.3 atmospheres pressure for 1 hour. The catalyst was removed by filtration through diatomaceous earth and the solvent removed by evaporation. The solid residue was suspended in ethyl acetate, collected by filtration and dried under vacuum to give 4-methoxy-3-(2-methoxyethoxy)aniline (6.1 g, 100%).
後処理
- customThe catalyst was removed by filtration through diatomaceous earth
- customthe solvent removed by evaporation
- filtrationcollected by filtration
- customdried under vacuum
出典と根拠
- ORDレコード
- ord-aadfa82b400f4cbfbc72208da66c4116
- 出典データセット
- uspto-grants-2004_10
- 特許番号
- US06809097B1
反応ノート
読み込み中…