Sulfuric Acid → 4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-thiazole
反応式
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH2:8])=[S:7])=[CH:4][CH:3]=1.[Cl:11][CH2:12][C:13]([CH2:15]Cl)=O.S(=O)(=O)(O)O>>[Cl:11][CH2:12][C:13]1[N:8]=[C:6]([C:5]2[CH:9]=[CH:10][C:2]([Cl:1])=[CH:3][CH:4]=2)[S:7][CH:15]=1参加物
4
実験手順
In analogy to the procedure described in example 4 a], 4-chlorothiobenzamide was reacted with 1,3-dichloroacetone followed by treatment with concentrated sulfuric acid to obtain 4-chloromethyl-2-(4-chloro-phenyl)-thiazole as colorless crystals.
出典と根拠
- ORDレコード
- ord-ee9f13dfa3e24067a6276b56dbad7bb0
- 出典データセット
- uspto-grants-2004_10
- 特許番号
- US06809110B2
反応ノート
読み込み中…