HCID 22712342、化合物 → HCID 22712345、化合物
反応式
[CH3:1][N:2]([CH3:14])[C:3]1[CH:8]=[CH:7][C:6]([Br:9])=[C:5]([N+:10]([O-])=O)[C:4]=1[CH3:13]>C1COCC1.[H][H].[Ni]>[Br:9][C:6]1[CH:7]=[CH:8][C:3]([N:2]([CH3:14])[CH3:1])=[C:4]([CH3:13])[C:5]=1[NH2:10]参加物
5
実験手順
15 g of N,N-dimethyl-4-bromo-2-methyl-3-nitroaniline is dissolved in about 200 ml of THF and hydrogenated at 20° C. under 5 bars pressure of hydrogen using Raney nickel as catalyst. 12 g of 2-bromo-5-dimethylamino-6-methylaniline is obtained as a brown oil.
出典と根拠
- ORDレコード
- ord-aa39f71d8db04dd4a0d2be9cc84c90e8
- 出典データセット
- uspto-grants-2003_08
- 特許番号
- US06602897B2
反応ノート
読み込み中…