反応式
C[O:2][C:3]1[CH:13]=[CH:12][C:6]2[CH2:7][CH2:8][NH:9][CH2:10][CH2:11][C:5]=2[CH:4]=1.[BrH:14]>>[BrH:14].[OH:2][C:3]1[CH:13]=[CH:12][C:6]2[CH2:7][CH2:8][NH:9][CH2:10][CH2:11][C:5]=2[CH:4]=1参加物
3
反応条件
- 温度
- 100 °C
実験手順
7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine (10 g) in 48% aqueous hydrobromic acid (350 ml) was allowed to stir at 100° C. for 4 h. The mixture was cooled to 20° C. then evaporated to dryness in vacuo to give the title compound (14.5 g) as a brown solid.
後処理
- temperatureThe mixture was cooled to 20° C.
- customthen evaporated to dryness in vacuo
出典と根拠
- ORDレコード
- ord-06c471aa95454f4dbe946f9057bfaef9
- 出典データセット
- uspto-grants-2003_08
- 特許番号
- US06605607B1
関連ノート
読み込み中…