HCID 12988784、化合物 → 1,2-Benzenediamine, 4-[2-(4-morpholinyl)ethoxy]-

HRID 395338ノート

反応式

HRID 395338 の反応式
[N:1]1([CH2:7][CH2:8][O:9][C:10]2[CH:15]=[CH:14][C:13]([NH2:16])=[C:12]([N+:17]([O-])=O)[CH:11]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1>CCO.[Pd]>[N:1]1([CH2:7][CH2:8][O:9][C:10]2[CH:11]=[C:12]([NH2:17])[C:13]([NH2:16])=[CH:14][CH:15]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1

参加物

4

反応物 1

HCID 12988784HCID 12988784、化合物

生成物 1

HCID 129887851,2-Benzenediamine, 4-[2-(4-morpholinyl)ethoxy]-

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

To a solution 4-(2-morpholin-4-ylethoxy)-2-nitrophenylamine (1.0 eq) in EtOH was added Pd/C (0.1 eq). The reaction vessel was repeatedly purged with nitrogen, then stirred under a hydrogen atmosphere (1 atm) for 18 hours. The product was filter ed through a Celite plug, and the plug washed with EtOH. The diamine was used without purification. LC/MS m/z 238.3 (MH+), Rf 0.295 minutes.

後処理

  1. customThe reaction vessel was repeatedly purged with nitrogen
  2. filtrationThe product was filter
  3. washthe plug washed with EtOH
  4. customThe diamine was used without purification

出典と根拠

ORDレコード
ord-f4ca8b85f75d47eaaf3115c77a1dab1e
出典データセット
uspto-grants-2003_08
特許番号
US06605617B2

反応ノート

読み込み中…