tert-Butyl hydroperoxide → Cyclohexanol cyclohexanone

HRID 397370

反応式

HRID 397370 の反応式
C(OO)(C)(C)C.S([O-])([O-])(=O)=O.[Na+].[Na+].[C:14]1(=[O:20])[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>C(#N)C.C1CCCCC1>[C:14]1(=[O:20])[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1.[CH:14]1([OH:20])[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1

参加物

6

反応物 3

HCID 6410tert-Butyl hydroperoxideHCID 7967CyclohexanoneHCID 24436Sodium Sulfate

生成物 1

HCID 22492587Cyclohexanol cyclohexanone

試薬・触媒・溶媒 2

HCID 6342Acetonitrile溶媒HCID 8078Cyclohexane溶媒2 回

実験手順

To an argon purged solution of Complex 3 (0.1 mM) in acetonitrile, cyclohexane (50 mM) was added followed by 20 mM of tert-butylhydroperoxide (t-BuOOH) (dissolved in di-t-butylether). The reaction mixture was maintained under an argon atmosphere for 30 min followed by the addition of an aqueous solution of sodium sulphate (0.4 M). The iron complex dissolved in the aqueous phase and the products (cyclohexane and cyclohexanone) were analysed by GC. Analyses yielded 0.5-1.5 mM of cyclohexanone +cyclohexanol (5-15 turnovers).

後処理

  1. temperatureThe reaction mixture was maintained under an argon atmosphere for 30 min
  2. dissolutionThe iron complex dissolved in the aqueous phase

出典と根拠

ORDレコード
ord-47d52450d6ea4d3dacc379a5126d1475
出典データセット
uspto-grants-2003_08
特許番号
US06610641B2

関連ノート

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