Ethyl 2-(4,4-dimethyl-2-cyclohexen-1-ylidene)acetate → (4,4-Dimethyl-cyclohexyl)-acetic acid ethyl ester
反応式
[CH3:1][C:2]1([CH3:14])[CH2:7][CH2:6][C:5](=[CH:8][C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH:4]=[CH:3]1>CO.[Pd]>[CH3:1][C:2]1([CH3:14])[CH2:3][CH2:4][CH:5]([CH2:8][C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH2:6][CH2:7]1参加物
4
実験手順
A solution of ethyl 2-(4,4-dimethyl-2-cyclohexene-1-ylidene)acetate (Preparation 13, 4.0 g, 21 mmol) in methanol (40 ml) was treated with 5% palladium on carbon, and the suspension was placed under an atmosphere of hydrogen (60 p.s.i.) at room temperature for 48 h. The mixture was filtered through a short pad of silica (40 g) and the filtrate was concentrated in vacuo to afford the title compound as a colourless oil (3.7 g, 91%).
後処理
- filtrationThe mixture was filtered through a short pad of silica (40 g)
- concentrationthe filtrate was concentrated in vacuo
出典と根拠
- ORDレコード
- ord-1fb8cb4c8fab46169484184badf6d66c
- 出典データセット
- uspto-grants-2003_08
- 特許番号
- US06610711B2
反応ノート
読み込み中…