Hydrochloric Acid → Ethyl cyclopropanecarboximidate hydrochloride

HRID 397948

反応式

HRID 397948 の反応式
[ClH:1].[CH:2]1([C:5]#[N:6])[CH2:4][CH2:3]1.[CH2:7]([O:9]CC)[CH3:8]>CCO>[ClH:1].[CH2:7]([O:9][C:5]([CH:2]1[CH2:4][CH2:3]1)=[NH:6])[CH3:8]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 79637Cyclopropanecarbonitrile

生成物 1

HCID 20026660Ethyl cyclopropanecarboximidate hydrochloride収率 59%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

反応条件

温度
0 °C

実験手順

A steady stream of HCl gas was slowly passed through a solution of cyclopropancarbonitril (25 g, 373 mmol) in EtOH (17.2 ml). After 15 h the reaction mixture was cooled to 0° C. and diethylether was added dropwise. The precipitated title compound was filtered and obtained as a colourless crystalline material (32.9 g, 220 mmol, 59%). MS: m/e=112.2 (M−H).

後処理

  1. customThe precipitated title compound
  2. filtrationwas filtered

出典と根拠

ORDレコード
ord-82b83684b24e4704b279c0b7d2caca4b
出典データセット
uspto-grants-2003_08
特許番号
US06610723B2

関連ノート

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