HCID 23000277、化合物 → 4-Methyl-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile
反応式
[C:1]([C:3]1[C:4]([CH3:12])=[C:5]2[C:9](=[N:10][CH:11]=1)[NH:8][CH2:7][CH2:6]2)#[N:2]>C(Cl)(Cl)Cl.[O-2].[O-2].[Mn+4]>[C:1]([C:3]1[C:4]([CH3:12])=[C:5]2[C:9](=[N:10][CH:11]=1)[NH:8][CH:7]=[CH:6]2)#[N:2]参加物
4
実験手順
A mixture of 5-cyano-4-methyl-7-azaindoline (52 mg, 0.33 mmol) and manganese dioxide (130 mg, 1.5 mmol) in chloroform (10 mL) was stirred for 16 h and then was filtered through celite, washing through with chloroform followed by methanol. The filtrate was evaporated in vacuo to give the title compound as a tan solid:
後処理
- filtrationwas filtered through celite
- washwashing through with chloroform
- customThe filtrate was evaporated in vacuo
出典と根拠
- ORDレコード
- ord-dd8fbfc54c8a4cd68855d8c458a08a9c
- 出典データセット
- uspto-grants-2003_08
- 特許番号
- US06610692B1
反応ノート
読み込み中…