Butylamine → N-butyl-2-methylaniline

反応式

[C:1]1([CH3:15])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1OS(C(F)(F)F)(=O)=O.[CH2:16]([NH2:20])[CH2:17][CH2:18][CH3:19]>>[CH2:16]([NH:20][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][C:1]=1[CH3:15])[CH2:17][CH2:18][CH3:19]

参加物

反応物 2

HCID 8007Butylamine

HCID 572025o-Tolyl Trifluoromethanesulfonate

生成物 1

HCID 11073747N-butyl-2-methylaniline収率 67%

実験手順

General procedure B using 55.1 mg (0.229 mmol) of o-tolyltriflate and 34.0 μl (0.344 mmol) of n-butylamine gave 67% yield of N-butyl-2-methylaniline after silica gel chromatograph using 5% ethyl acetate in hexanes.

出典と根拠

ORDレコード: ord-fdcf88cbec6c46eeba2949b035418134
出典データセット: uspto-grants-1998_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05817877

反応ノート

読み込み中…