Water → 3-(4-Aminophenyl)propionic acid
反応式
O.[N+:2]([C:5]1[CH:15]=[CH:14][C:8]([CH:9]=[CH:10][C:11]([OH:13])=[O:12])=[CH:7][CH:6]=1)([O-])=O.[H][H]>[Pd].CO>[NH2:2][C:5]1[CH:6]=[CH:7][C:8]([CH2:9][CH2:10][C:11]([OH:13])=[O:12])=[CH:14][CH:15]=1参加物
6
実験手順
15 g of palladium on carbon (10% and 30 ml of water are added to a mixture of 155 g of 4-nitrocinnamic acid in 1 l of methanol, and hydrogenation is carried out at room temperature under 3 bar until no further hydrogen is taken up, after about 2 hours. After filtration and evaporation of the solvent in a rotary evaporator, residual water is removed by twice adding 300 ml portions of toluene and distilling off the solvent in a rotary evaporator.
後処理
- filtrationAfter filtration and evaporation of the solvent
- customin a rotary evaporator, residual water
- customis removed
- additionby twice adding 300 ml portions of toluene
- distillationdistilling off the solvent
- customin a rotary evaporator
出典と根拠
- ORDレコード
- ord-080107e432b24871a28213b866e90934
- 出典データセット
- uspto-grants-1998_10
- 特許番号
- US05821240
反応ノート
読み込み中…