Dimethylformamide → 2,6-Dibromo-1,4-phenylenediamine
反応式
[Br:1][C:2]1[CH:8]=[C:7]([N+:9]([O-])=O)[CH:6]=[C:5]([Br:12])[C:3]=1[NH2:4].C(OCC)(=O)C.CN(C)C=O.C(Cl)Cl>C(O)C.[Pt]>[NH2:9][C:7]1[CH:8]=[C:2]([Br:1])[C:3]([NH2:4])=[C:5]([Br:12])[CH:6]=1参加物
7
実験手順
20 g of 2,6-Dibromo-4-nitroaniline are taken up in 250 ml of ethanol, 250 ml of ethyl acetate, 100 ml of dimethylformamide and 90 ml of methylene chloride and, after addition of 3.3 g of 5% moist platinum/active carbon catalyst, hydrogenated at room temperature under 50 psi for one hour. The solvent is then distilled off in a rotary evaporator, and the residue is triturated with diethyl ether, filtered off with suction and washed several times with petroleum ether.
後処理
- distillationThe solvent is then distilled off in a rotary evaporator
- customthe residue is triturated with diethyl ether
- filtrationfiltered off with suction
- washwashed several times with petroleum ether
出典と根拠
- ORDレコード
- ord-0ad8c440815246b7b935f8ec8b1a95bf
- 出典データセット
- uspto-grants-1998_10
- 特許番号
- US05821240
反応ノート
読み込み中…