Hydrochloric Acid → 4-Ethoxy-3,5-dimethoxybenzoic acid
反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([O:16][CH3:17])[C:12]=1[O:13][CH2:14][CH3:15])[C:6]([O:8]C)=[O:7].[OH-].[Na+].Cl>CO>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([O:16][CH3:17])[C:12]=1[O:13][CH2:14][CH3:15])[C:6]([OH:8])=[O:7]参加物
5
実験手順
Combine methyl 3,5-dimethoxy-4-ethoxy-benzoate (2.13 g, 9,421 mmol) and methanol (30 mL). Add a 1M aqueous solution of sodium hydroxide (50 mL, 50 mmol). After 1 hour, acidify the reaction mixture using a 1M aqueous hydrochloric acid solution, extract with ethyl acetate. Dry the organic layer over MgSO4, filtered and evaporated in vacuo to give the title compound.
後処理
- extractionextract with ethyl acetate
- dry with materialDry the organic layer over MgSO4
- filtrationfiltered
- customevaporated in vacuo
出典と根拠
- ORDレコード
- ord-aaaa39689fe84263b7a454a741ea3aed
- 出典データセット
- uspto-grants-1998_10
- 特許番号
- US05824690
反応ノート
読み込み中…