Hydrochloric Acid → 4-Chloro-N,N-dimethylbenzamide
反応式
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][CH:3]=1.[CH3:11][NH:12][CH3:13].N1C=CC=CC=1.Cl>C1(C)C=CC=CC=1>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([N:12]([CH3:13])[CH3:11])=[O:7])=[CH:4][CH:3]=1参加物
6
実験手順
The procedure of Example 13 is followed, but the endcapper is 4-chloro-N,N-dimethylbenzamide (0.20 g, 1.09 mmol) to yield the amido-functionalized macromonomer. 4-Chloro-N,N-dimethylbenzamide is prepared by reacting 4-chlorobenzoyl chloride with dimethylamine in toluene with some pyridine (1 mol equivalent per acid chloride) to trap the HCl that is evolved. After aqueous extraction of the pyridinium salt and any excess starting materials, the product is crystallized from the toluene solution.
後処理
- extractionAfter aqueous extraction of the pyridinium salt
- customany excess starting materials, the product is crystallized from the toluene solution
出典と根拠
- ORDレコード
- ord-1ef2014c8403494082714a8f3018b0c9
- 出典データセット
- uspto-grants-1998_10
- 特許番号
- US05827927
反応ノート
読み込み中…