Dichloromethane → 2-Chloro-5-(chlorosulfonyl)benzoyl chloride

HRID 400508

反応式

HRID 400508 の反応式
[Cl:1][C:2]1[CH:10]=[CH:9][C:8]([S:11]([Cl:14])(=[O:13])=[O:12])=[CH:7][C:3]=1[C:4](O)=[O:5].[Cl:15]CCl.C(Cl)(=O)C(Cl)=O>CN(C)C=O>[Cl:1][C:2]1[CH:10]=[CH:9][C:8]([S:11]([Cl:14])(=[O:13])=[O:12])=[CH:7][C:3]=1[C:4]([Cl:15])=[O:5]

参加物

5

反応物 3

HCID 6344DichloromethaneHCID 65578Oxalyl chlorideHCID 67306Benzoic acid, 2-chloro-5-(chlorosulfonyl)-

生成物 1

HCID 545501992-Chloro-5-(chlorosulfonyl)benzoyl chloride

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

To 2-chloro-5-(chlorosulfonyl)benzoic acid (0.51 g, 2.0 mmol) was added dichloromethane (10 mL), oxalyl chloride (1.5 mL) and one small drop of N,N-dimethylformamide. The mixture was stirred at room temperature for 3 days. The mixture was then concentrated until oxalyl chloride was gone to give 2-chloro-5-(chlorosulfonyl)benzoyl chloride. The residue was used without purification.

後処理

  1. concentrationThe mixture was then concentrated until oxalyl chloride

出典と根拠

ORDレコード
ord-cc8def7ac8604b05b968bc3109e10fae
出典データセット
uspto-grants-2014_06
特許番号
US08741899B2

関連ノート

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