1,1'-Carbonyldiimidazole → Oxazol-5-ylmethyl 1H-imidazole-1-carboxylate
反応式
[O:1]1[C:5]([CH2:6][OH:7])=[CH:4][N:3]=[CH:2]1.[C:8](N1C=CN=C1)([N:10]1[CH:14]=[CH:13][N:12]=[CH:11]1)=[O:9]>C(Cl)Cl>[N:10]1([C:8]([O:7][CH2:6][C:5]2[O:1][CH:2]=[N:3][CH:4]=2)=[O:9])[CH:14]=[CH:13][N:12]=[CH:11]1参加物
4
実験手順
Oxazol-5-ylmethanol (0.15 g, 1.51 mmol) in anhydrous CH2Cl2 (5 mL) under a dry N2 atmosphere was treated with 1,1′-carbonyldiimidazole (0.20 g, 1.23 mmol) at ambient temperature and stirred for 2 hours to provide the title compound in a solution of CH2Cl2 which was used in subsequent Examples without further manipulation.
出典と根拠
- ORDレコード
- ord-ff68af3ebdda4730a9872325473d1477
- 出典データセット
- uspto-grants-2014_06
- 特許番号
- US08741938B2
反応ノート
読み込み中…