4-(Dimethylamino)Benzaldehyde → n-(5-Carboxypentyl)-4-(4-(dimethylamino)styryl)pyridinium bromide

HRID 40447

反応式

HRID 40447 の反応式
[CH3:1][N:2]([C:4]1[CH:9]=[CH:8][C:7]([CH:10]=O)=[CH:6][CH:5]=1)[CH3:3].[Br-:12].[C:13]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][N+:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1C)([OH:15])=[O:14].N1CCCC[CH2:29]1>C(O)C>[Br-:12].[C:13]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][N+:21]1[CH:22]=[CH:23][C:24]([CH:29]=[CH:10][C:7]2[CH:6]=[CH:5][C:4]([N:2]([CH3:1])[CH3:3])=[CH:9][CH:8]=2)=[CH:25][CH:26]=1)([OH:15])=[O:14]

参加物

5

反応物 3

HCID 74794-(Dimethylamino)BenzaldehydeHCID 8082PiperidineHCID 666435031-(5-Carboxy-pentyl)-2-methyl-pyridinium bromide

生成物 1

HCID 66643380n-(5-Carboxypentyl)-4-(4-(dimethylamino)styryl)pyridinium bromide

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

反応条件

温度
60 °C

実験手順

A mixture of 4-N,N-dimethylaminobenzaldehyde (3 g, 20 mmoles), N-(5-carboxy-pentyl)picolinium bromide (5.6 g, 20 mmoles) and piperidine (2 mL) in ethanol (100 mL) was heated at 60° C. overnight. The mixture was evaporated to dryness in vacuo. The residue was redissolved in methanol and then precipitated with ether to give the product (6.7 g).

後処理

  1. customThe mixture was evaporated to dryness in vacuo
  2. dissolutionThe residue was redissolved in methanol
  3. customprecipitated with ether

出典と根拠

ORDレコード
ord-af6963a81e4745939b0548827d31456a
出典データセット
uspto-grants-2013_09
特許番号
US08530195B2

関連ノート

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