Hydrogen Bromide → HCID 49758827、化合物

HRID 40557

反応式

HRID 40557 の反応式
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([C@@H:9]([NH2:11])[CH3:10])=[CH:5][CH:4]=1.[BrH:12]>>[BrH:12].[NH2:11][C@H:9]([C:6]1[CH:7]=[CH:8][C:3]([OH:2])=[CH:4][CH:5]=1)[CH3:10]

参加物

3

反応物 2

HCID 260Hydrogen BromideHCID 793467(S)-1-(4-Methoxyphenyl)ethylamine

生成物 1

HCID 49758827HCID 49758827、化合物

反応条件

温度
100 °C

実験手順

To 11.0 g (72.7 mmol) (S)-1-(4-methoxy-phenyl)-ethylamine is added carefully 30 mL HBr (30% in HOAc). The mixture is stirred at 100° C. for 4 h. After cooling down to r.t., the solvent is removed in vacuo and the residue is dried in vacuo. The resulting product is used without further purification.

後処理

  1. temperatureAfter cooling down to r.t.
  2. customthe solvent is removed in vacuo
  3. customthe residue is dried in vacuo
  4. customThe resulting product is used without further purification

出典と根拠

ORDレコード
ord-388579f90eae45a381a7f25c01287e36
出典データセット
uspto-grants-2013_09
特許番号
US08530460B2

関連ノート

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