化工社化工社 化学情報印刷レポート · 研究参考用
Benzo(F)Quinoline → Mls002703342
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzo(F)Quinoline | HCID 6796 | — |
| 反応物 | Benzoyl chloride | HCID 7412 | — |
| 反応物 | Potassium Cyanide | HCID 9032 | — |
| 反応物 | Water methylene chloride | HCID 21908982 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Mls002703342 | HCID 262649 | — |
反応手順
648 μl (5.58 mmol) benzoyl chloride was added to a two phase system of water/methylene chloride over a period of two hours. These two layers contain 500 mg (2.79 mmol) of benzo(f)chinolin in the methylene chloride layer and 545 mg (8.37 mmol) KCN in water. Stirring was continued for 6 hours. The organic phase was separated and washed with water, 5% hydrochloric acid, water, 5% NaOH solution, and again with water. After drying over magnesium sulfate, the solution was evaporated to dryness.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08753641B2 |
| 出典データセット | uspto-grants-2014_06 |
| ORD ID | ord-efdf6f83041f43f2a404661c530990f1 |
| 出典メモ | uspto-grants-2014_06 |