反应详情

648 μl (5.58 mmol) benzoyl chloride was added to a two phase system of water/methylene chloride over a period of two hours. These two layers contain 500 mg (2.79 mmol) of benzo(f)chinolin in the methylene chloride layer and 545 mg (8.37 mmol) KCN in water. Stirring was continued for 6 hours. The organic phase was separated and washed with water, 5% hydrochloric acid, water, 5% NaOH solution, and again with water. After drying over magnesium sulfate, the solution was evaporated to dryness.

1. customThe organic phase was separated
2. washwashed with water, 5% hydrochloric acid, water, 5% NaOH solution
3. dry with materialAfter drying over magnesium sulfate
4. customthe solution was evaporated to dryness