HCID 58117567、化合物 → (S)-5-amino-1-propylpiperidin-2-one
反応式
C([N:8](CC1C=CC=CC=1)[C@@H:9]1[CH2:14][N:13]([CH2:15][CH2:16][CH3:17])[C:12](=[O:18])[CH2:11][CH2:10]1)C1C=CC=CC=1>CO.[Pd]>[NH2:8][C@@H:9]1[CH2:14][N:13]([CH2:15][CH2:16][CH3:17])[C:12](=[O:18])[CH2:11][CH2:10]1参加物
4
実験手順
0.569 g (S)-5-dibenzylamino-1-propylpiperidin-2-one are placed in 25 ml of methanol and hydrogenated with 0.150 g Pd/C 10% at a pressure of 3 bar and a temperature of 60° C. After 19 hours the catalyst is suction filtered and the filtrate is evaporated to dryness. 0.217 g of the product are obtained as an oil.
後処理
- customa temperature of 60° C
- filtrationsuction filtered
- customthe filtrate is evaporated to dryness
出典と根拠
- ORDレコード
- ord-e8b0e500918d4f5398e2f5c1f4dd1bf2
- 出典データセット
- uspto-grants-2014_06
- 特許番号
- US08754073B2
反応ノート
読み込み中…