4-Methoxyphenol → 4-Methoxycyclohexanol (cis,trans)

HRID 406027

反応式

HRID 406027 の反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1.[H][H]>C(O)C>[CH3:1][O:2][CH:3]1[CH2:8][CH2:7][CH:6]([OH:9])[CH2:5][CH2:4]1

参加物

4

反応物 2

HCID 90154-MethoxyphenolHCID 178418361HCID 178418361、化合物

生成物 1

HCID 1403324-Methoxycyclohexanol (cis,trans)

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

4-Methoxyphenol (100 g) in ethanol (759 ml) was hydrogenated under 50 psi hydrogen using Nishimura catalyst (10.0 g) at rt for 4.5 h. The catalyst was filtered off; the solvent was removed in vacuo to yield the desired product as 95% pure yellowish liquid.

後処理

  1. customat rt
  2. customfor 4.5 h
  3. filtrationThe catalyst was filtered off
  4. customthe solvent was removed in vacuo

出典と根拠

ORDレコード
ord-66c84cbcff4b405b833f38f35bbb2adf
出典データセット
uspto-grants-2014_06
特許番号
US08754079B2

関連ノート

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