2-Isopropylpyridine → 1-Oxo-2-(propan-2-yl)-1lambda~5~-pyridine
反応式
[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N:5]=1)([CH3:3])[CH3:2].C1C=C(Cl)C=C(C(OO)=[O:18])C=1>C(Cl)Cl>[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N+:5]=1[O-:18])([CH3:3])[CH3:2]参加物
4
実験手順
A mixture of isopropylpyridine (2.1 g, 17.75 mmol) and m-CPBA (5.0 g, 1.3 eq.) in CH2Cl2 was stirred overnight at room temperature. Then, the reaction mixture was diluted with CH2Cl2 (twice the volume) and successively washed with aqueous sodium bicarbonate (twice) and brine, dried (Na2SO4) and evaporated to give 2.0 g (85%) of the title compound 104.
後処理
- washsuccessively washed with aqueous sodium bicarbonate (twice) and brine
- dry with materialdried (Na2SO4)
- customevaporated
出典と根拠
- ORDレコード
- ord-3b5a2279c0dd4dc4be59883f719edeea
- 出典データセット
- uspto-grants-2014_06
- 特許番号
- US08754106B2
反応ノート
読み込み中…