Methylamine → HCID 178462848、化合物

HRID 40761

反応式

HRID 40761 の反応式
[C:1]1(=[O:17])[N:5]([CH2:6][CH2:7][S:8](Cl)(=[O:10])=[O:9])[C:4](=[O:12])[C:3]2=[CH:13][CH:14]=[CH:15][CH:16]=[C:2]12.[CH3:18][NH2:19]>C1COCC1.O>[C:4]1(=[O:12])[N:5]([CH2:6][CH3:7])[C:1](=[O:17])[C:2]2=[CH:16][CH:15]=[CH:14][CH:13]=[C:3]12.[CH3:18][NH:19][SH:8](=[O:9])=[O:10]

参加物

5

反応物 2

HCID 6329MethylamineHCID 3087392-Phthalimidoethanesulfonyl chloride

生成物 1

HCID 178462848HCID 178462848、化合物

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 8028Tetrahydrofuran溶媒

実験手順

2-Phthalimidoethanesulfonyl chloride (2.0 g) was added portion wise to a solution of 2.0 M methylamine in THF (15 ml) and the solution obtained this way was stirred at room temperature. After 48 hours the reaction mixture was poured in water (50 ml) causing the title compound to precipitate. The product was collected by filtration and recrystallized from EtOH:water, 50:1 to yield: 1.04 g (48%) of the desired product as a solid.

後処理

  1. customthe solution obtained this way

出典と根拠

ORDレコード
ord-15af8745e0104771a2b59e6f0ad73bcc
出典データセット
uspto-grants-2013_09
特許番号
US08530486B2

関連ノート

読み込み中…