Oxalyl chloride → HCID 59625951、化合物
反応式
[Cl:1][C:2]1[CH:17]=[CH:16][C:5]2[S:6][C:7]([C:13](O)=[O:14])=[C:8]([C:9]([F:12])([F:11])[F:10])[C:4]=2[CH:3]=1.C(Cl)(C([Cl:22])=O)=O>C(Cl)Cl.CN(C=O)C>[Cl:1][C:2]1[CH:17]=[CH:16][C:5]2[S:6][C:7]([C:13]([Cl:22])=[O:14])=[C:8]([C:9]([F:12])([F:11])[F:10])[C:4]=2[CH:3]=1参加物
5
実験手順
To compound 18f in CH2Cl2 (5 mL) at room temperature was added (COCl)2, followed by 2 drops of DMF. The reaction mixture was stirred at room temperature for 18 h. The reaction mixture was then concentrated to give compound 18g.
後処理
- concentrationThe reaction mixture was then concentrated
出典と根拠
- ORDレコード
- ord-33489a48cd394b749c728bb541670be1
- 出典データセット
- uspto-grants-2014_06
- 特許番号
- US08759533B2
反応ノート
読み込み中…