Ethanol → 5-Bromo-2-[3,4-dihydro-1(2H)-quinolinyl]aniline
反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[CH2:11][CH2:10][CH2:9]2)=[C:4]([N+:18]([O-])=O)[CH:3]=1.C(O)C>C1C=CC=CC=1.[Pt]>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[CH2:11][CH2:10][CH2:9]2)=[C:4]([NH2:18])[CH:3]=1参加物
5
実験手順
1-(4-Bromo-2-nitrophenyl)-1,2,3,4-tetrahydroquinoline (11.6 g, 0.035 mole) was dissolved in benzene (125 ml), and ethanol added (75 ml), followed by 1% platinum-on-charcoal (0.40 g). The mixture was shaken under an initial pressure of 56 psi for 6.5 hours. The mixture was filtered and the filtrate was evaporated at 50° C. under vacuum to provide 10.6 g (100%) of product, as a gum.
後処理
- filtrationThe mixture was filtered
- customthe filtrate was evaporated at 50° C. under vacuum
出典と根拠
- ORDレコード
- ord-3ebfa7b3c5cb47f9828c4e52f9823e21
- 出典データセット
- uspto-grants-1988_02
- 特許番号
- US04723003
反応ノート
読み込み中…