化工社化工社 化学情報印刷レポート · 研究参考用
Methylamine → 4-(Methylamino)-3-nitrobenzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methylamine | HCID 6329 | — |
| 反応物 | 4-Fluoro-3-nitrobenzoic acid | HCID 67987 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 4-(Methylamino)-3-nitrobenzoic acid | HCID 283475 | — |
反応手順
4-Methylamino-3-nitro-benzoic acid (825 mg) was prepared by following General Procedure A starting from 4-fluoro-3-nitro-benzoic acid (1.0 g) and methylamine (2 M in THF, 8.1 mL) in THF. The crude product was used in the next step without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08759535B2 |
| 出典データセット | uspto-grants-2014_06 |
| ORD ID | ord-705eeba1d51b4124a7575f0951cb9830 |
| 出典メモ | uspto-grants-2014_06 |