Methylamine → 3-(Methylamino)-4-nitrobenzoic acid

HRID 410757ノート

反応式

HRID 410757 の反応式
Cl[C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[N+:11]([O-:13])=[O:12])[C:5]([OH:7])=[O:6].[CH3:14][NH2:15]>C1COCC1>[CH3:14][NH:15][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[N+:11]([O-:13])=[O:12])[C:5]([OH:7])=[O:6]

参加物

4

反応物 2

HCID 6329MethylamineHCID 5209533-Chloro-4-nitrobenzoic acid

生成物 1

HCID 221846233-(Methylamino)-4-nitrobenzoic acid

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

3-Methylamino-4-nitro-benzoic acid (1.1 g) was prepared by following General Procedure A starting from 3-chloro-4-nitro-benzoic acid (1.0 g) and methylamine (2 M in THF, 8.1 mL) in THF. The crude product was used in the next step without further purification.

後処理

  1. customThe crude product was used in the next step without further purification

出典と根拠

ORDレコード
ord-f69696e8839d43f3a39a54262b77c284
出典データセット
uspto-grants-2014_06
特許番号
US08759535B2

反応ノート

読み込み中…