Methylamine → 2-Fluoro-4-(methylamino)-5-nitrobenzoic acid
反応式
[F:1][C:2]1[CH:10]=[C:9](F)[C:8]([N+:12]([O-:14])=[O:13])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[CH3:15][NH2:16]>C1COCC1>[F:1][C:2]1[CH:10]=[C:9]([NH:16][CH3:15])[C:8]([N+:12]([O-:14])=[O:13])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5]参加物
4
実験手順
2-Fluoro-4-methylamino-5-nitro-benzoic acid (750 mg) was prepared by following General Procedure A starting from 2,4-difluoro-5-nitro-benzoic acid (1.0 g) and methylamine (2 M in THF, 2.46 mL) in THF.
出典と根拠
- ORDレコード
- ord-23bfe7fce064480ca62974a04a9828e1
- 出典データセット
- uspto-grants-2014_06
- 特許番号
- US08759535B2
反応ノート
読み込み中…