6-Methylamino-5-nitro-nicotinic acid ethyl ester → 5-Amino-6-methylamino-nicotinic acid ethyl ester
反応式
[CH2:1]([O:3][C:4](=[O:16])[C:5]1[CH:10]=[C:9]([N+:11]([O-])=O)[C:8]([NH:14][CH3:15])=[N:7][CH:6]=1)[CH3:2]>[Pd]>[CH2:1]([O:3][C:4](=[O:16])[C:5]1[CH:10]=[C:9]([NH2:11])[C:8]([NH:14][CH3:15])=[N:7][CH:6]=1)[CH3:2]参加物
3
実験手順
5-Amino-6-methylamino-nicotinic acid ethyl ester (723 mg) was prepared by following General Procedure B starting from 6-methylamino-5-nitro-nicotinic acid ethyl ester (911 mg) and Pd/C (10% by weight, 90 mg). The crude product was used in the next step without further purification.
後処理
- customThe crude product was used in the next step without further purification
出典と根拠
- ORDレコード
- ord-a4c38adfc2dc4e5ba655597fa0fdc514
- 出典データセット
- uspto-grants-2014_06
- 特許番号
- US08759535B2
反応ノート
読み込み中…