Methyl 4-[(2-methylpropyl)amino]-3-nitrobenzoate → HCID 50989117、化合物
反応式
[CH3:1][O:2][C:3](=[O:18])[C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH2:11][CH:12]([CH3:14])[CH3:13])=[C:6]([N+:15]([O-])=O)[CH:5]=1>CO.CCOC(C)=O.[Pd]>[CH3:1][O:2][C:3](=[O:18])[C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH2:11][CH:12]([CH3:13])[CH3:14])=[C:6]([NH2:15])[CH:5]=1参加物
4
実験手順
3-Amino-4-isobutylamino-benzoic acid methyl ester (790.0 mg) was prepared by following General Procedure B starting from 4-isobutylamino-3-nitro-benzoic acid methyl ester (950.0 mg) and Pd/C (20% by weight, 190.0 mg) in MeOH:EtOAc (1:1, 10.0 mL). The crude product was used in the next step without further purification.
後処理
- customThe crude product was used in the next step without further purification
出典と根拠
- ORDレコード
- ord-ada11378a3964c469d379ed06b23a675
- 出典データセット
- uspto-grants-2014_06
- 特許番号
- US08759535B2
反応ノート
読み込み中…