Acetic Anhydride → 1-Acetyl-7-methylindoline

HRID 411279

反応式

HRID 411279 の反応式
[CH3:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][CH2:8][CH2:7]2.[C:11](OC(=O)C)(=[O:13])[CH3:12]>>[C:11]([N:9]1[C:10]2[C:6](=[CH:5][CH:4]=[CH:3][C:2]=2[CH3:1])[CH2:7][CH2:8]1)(=[O:13])[CH3:12]

参加物

3

反応物 2

HCID 7918Acetic AnhydrideHCID 123777887-Methyl-2,3-dihydro-1H-indole

生成物 1

HCID 143613661-Acetyl-7-methylindoline

実験手順

A solution of 7-methylindoline (10.2 g) in acetic anhydride (25 ml) was refluxed for 30 min. After cooling, the reaction solution was poured into ice water (250 ml) and the resulting crystal was filtered by means of suction, heated and vacuum dried to yield the end product (11.7 g).

後処理

  1. temperatureAfter cooling
  2. filtrationthe resulting crystal was filtered by means of suction
  3. temperatureheated
  4. customvacuum dried

出典と根拠

ORDレコード
ord-532146205184410b96c1b186bb23c4a5
出典データセット
uspto-grants-2003_05
特許番号
US06559149B1

関連ノート

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