Water → N,N'-Di-tert-butoxycarbonyl-7-[1-(2-hydroxyethyl)piperidin-4-ylmethoxy]-1,2,3,4-tetrahydroisoquinoline-2-carboxamidine

反応式

C([O:3][C:4](=O)[CH2:5][N:6]1[CH2:11][CH2:10][CH:9]([CH2:12][O:13][C:14]2[CH:23]=[C:22]3[C:17]([CH2:18][CH2:19][N:20]([C:24](=[N:33][C:34]([O:36][C:37]([CH3:40])([CH3:39])[CH3:38])=[O:35])[NH:25][C:26]([O:28][C:29]([CH3:32])([CH3:31])[CH3:30])=[O:27])[CH2:21]3)=[CH:16][CH:15]=2)[CH2:8][CH2:7]1)C.[BH4-].[Li+].O>O1CCCC1.CO>[C:37]([O:36][C:34]([NH:33][C:24]([N:20]1[CH2:19][CH2:18][C:17]2[C:22](=[CH:23][C:14]([O:13][CH2:12][CH:9]3[CH2:8][CH2:7][N:6]([CH2:5][CH2:4][OH:3])[CH2:11][CH2:10]3)=[CH:15][CH:16]=2)[CH2:21]1)=[N:25][C:26]([O:28][C:29]([CH3:32])([CH3:31])[CH3:30])=[O:27])=[O:35])([CH3:38])([CH3:39])[CH3:40]