Glycine, N-acetyl-N-phenyl- → 5-{N'-(N-acetyl-N-phenylglycinyl)-L-alaninyl}-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one

HRID 413877

反応式

HRID 413877 の反応式
[C:1]([N:4]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[CH2:5][C:6]([OH:8])=O)(=[O:3])[CH3:2].[NH2:15][C@H:16]([C:18]([N:20]1[C:26](=[O:27])[CH:25]([CH3:28])[C:24]2[CH:29]=[CH:30][CH:31]=[CH:32][C:23]=2[C:22]2[C:33]([NH2:37])=[CH:34][CH:35]=[CH:36][C:21]1=2)=[O:19])[CH3:17]>>[C:1]([N:4]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[CH2:5][C:6]([NH:15][C@H:16]([C:18]([N:20]1[C:26](=[O:27])[CH:25]([CH3:28])[C:24]2[CH:29]=[CH:30][CH:31]=[CH:32][C:23]=2[C:22]2[C:33]([NH2:37])=[CH:34][CH:35]=[CH:36][C:21]1=2)=[O:19])[CH3:17])=[O:8])(=[O:3])[CH3:2]

参加物

3

反応物 2

HCID 68483Glycine, N-acetyl-N-phenyl-HCID 697363355-(L-alaninyl)-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one

生成物 1

HCID 865926055-{N'-(N-acetyl-N-phenylglycinyl)-L-alaninyl}-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one

実験手順

Following one or more of the general procedures outlined above, using acetyl-N-phenylglycine and 5-(L-alaninyl)-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one, as described in Example 7-B, the title compound was prepared. The molecular weight as determined by mass spectrometry (FD) was: 485 (M+H).

出典と根拠

ORDレコード
ord-7e257ba982834a7eba47fb77cb67c498
出典データセット
uspto-grants-2003_05
特許番号
US06569851B1

関連ノート

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