Dichloromethane → 1-Chloro-4-acetyl-cyclohexene

HRID 414649

反応式

HRID 414649 の反応式
[CH:1]([C:3]([CH3:5])=[O:4])=[CH2:2].[Cl-].[Al+3].[Cl-].[Cl-].C(Cl)Cl.[CH2:13]=[CH:14][C:15]([Cl:17])=[CH2:16]>O>[Cl:17][C:15]1[CH2:14][CH2:13][CH:1]([C:3](=[O:4])[CH3:5])[CH2:2][CH:16]=1

参加物

6

反応物 4

HCID 6344DichloromethaneHCID 6570Methyl vinyl ketoneHCID 31369ChloropreneHCID 6451240Aluminum(III) Chloride

生成物 1

HCID 143656601-Chloro-4-acetyl-cyclohexene

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
25 °C

実験手順

To a solution of 98.1 parts of methyl vinyl ketone, 187 parts of anhydrous aluminum chloride and 1980 parts of methylene chloride was added 123 parts of chloroprene and the mixture was stirred at 25° C. for three hours and left standing for another 16 hours. Water was added to the reaction mixture and the organic layer was washed with 5% hydrochloric acid. Distillation gave a center cut of 61 parts of 1-chloro-4-acetyl-cyclohexene (125°-6° C./20 mm Hg). Reference: A. A. Petrov and N. P. Sopov, CA 42, 1910h (1948).

後処理

  1. waitleft
  2. waitstanding for another 16 hours
  3. washthe organic layer was washed with 5% hydrochloric acid
  4. distillationDistillation

出典と根拠

ORDレコード
ord-19e3802694574392bda66521ea4de726
出典データセット
uspto-grants-1988_12
特許番号
US04792618

関連ノート

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