Thionyl Chloride → 5-(Tetrazol-1-yl)-valeric acid chloride

HRID 414739ノート

反応式

HRID 414739 の反応式
[N:1]1([CH2:6][CH2:7][CH2:8][CH2:9][C:10]([OH:12])=O)[CH:5]=[N:4][N:3]=[N:2]1.S(Cl)([Cl:15])=O>C1C=CC=CC=1.CN(C=O)C>[N:1]1([CH2:6][CH2:7][CH2:8][CH2:9][C:10]([Cl:15])=[O:12])[CH:5]=[N:4][N:3]=[N:2]1

参加物

5

反応物 2

HCID 24386Thionyl ChlorideHCID 212802905-(1H-Tetrazol-1-yl)pentanoic acid

生成物 1

HCID 178034065-(Tetrazol-1-yl)-valeric acid chloride

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide触媒HCID 241Benzene溶媒

実験手順

1 g of 5-(tetrazol-1-yl)-valeric acid in 12 ml of absolute benzene is heated at reflux temperature for 20 minutes with 0.6 ml of thionyl chloride and 2 drops of DMF. After concentration by evaporation under reduced pressure, the title compound is obtained.

後処理

  1. concentrationAfter concentration
  2. customby evaporation under reduced pressure

出典と根拠

ORDレコード
ord-32e5de1ea3664904b0df90faaf844a44
出典データセット
uspto-grants-1988_12
特許番号
US04794109

反応ノート

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