Trifluoroacetic acid → 2-(4-(3-(5-(4-Bromophenyl)thien-2-yl)-3-oxopropyl)-2,3-dichlorophenoxy)-2-methylpropanoic acid
反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[S:12][C:11]([C:13](=[O:35])[CH2:14][CH2:15][C:16]3[CH:32]=[CH:31][C:19]([O:20][C:21]([CH3:30])([CH3:29])[C:22]([O:24]C(C)(C)C)=[O:23])=[C:18]([Cl:33])[C:17]=3[Cl:34])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.FC(F)(F)C(O)=O>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[S:12][C:11]([C:13](=[O:35])[CH2:14][CH2:15][C:16]3[CH:32]=[CH:31][C:19]([O:20][C:21]([CH3:30])([CH3:29])[C:22]([OH:24])=[O:23])=[C:18]([Cl:33])[C:17]=3[Cl:34])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1参加物
3
実験手順
2-(4-(3-(5-(4-Bromophenyl)thien-2-yl)-3-oxopropyl)-2,3-dichlorophenoxy)-2-methylpropanoic acid is prepared from tert-butyl 2-(4-(3-(5-(4-bromophenyl)thien-2-yl)-3-oxopropyl)-2,3-dichlorophenoxy)-2-methylpropanoate according to general procedure E using 38 equivalents of trifluoroacetic acid.
出典と根拠
- ORDレコード
- ord-4ac46c4292364579ae6b3616fb05ed57
- 出典データセット