Homoallyl bromide → Diethyl 3-butenylphosphonate

HRID 417171ノート

反応式

HRID 417171 の反応式
Br[CH2:2][CH2:3][CH:4]=[CH2:5].[P:6]([O:13]CC)([O:10][CH2:11][CH3:12])[O:7][CH2:8][CH3:9]>C(Cl)(Cl)Cl>[CH2:2]([P:6](=[O:13])([O:10][CH2:11][CH3:12])[O:7][CH2:8][CH3:9])[CH2:3][CH:4]=[CH2:5]

参加物

4

反応物 2

HCID 21241Homoallyl bromideHCID 31215Triethyl phosphite

生成物 1

HCID 10997850Diethyl 3-butenylphosphonate

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

1-bromo-3-butene (39.0 mmol) and triethyl phosphite (1 g, 6 mmol) were dissolved and reacted in CHCl3 (30 mL). Then, the reaction solution was refluxed for 12 hours, cooled to room temperature and filtered through a glass filter. Chloroform (CHCl3) was completely removed from the solution under vacuum to thereby give an oily compound as the title compound. The 1H NMR results of the compound thus obtained are given as follows.

後処理

  1. temperatureThen, the reaction solution was refluxed for 12 hours
  2. filtrationfiltered through a glass
  3. filtrationfilter
  4. customChloroform (CHCl3) was completely removed from the solution under vacuum

出典と根拠

ORDレコード
ord-4a261f2dbf654a348991f1f703983f8c
出典データセット
uspto-grants-2012_01
特許番号
US08089682B2

反応ノート

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