HCID 58455289、化合物 → 1,3-Dihydroxypropan-2-yl phenyl succinate

HRID 41827ノート

反応式

HRID 41827 の反応式
[C:1]([O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)(=[O:19])[CH2:2][CH2:3][C:4]([O:6][CH:7]1[CH2:12][O:11]C(C2C=CC=CC=2)[O:9][CH2:8]1)=[O:5]>C(O)C.[Pd]>[C:4]([O:6][CH:7]([CH2:12][OH:11])[CH2:8][OH:9])(=[O:5])[CH2:3][CH2:2][C:1]([O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:19]

参加物

4

反応物 1

HCID 58455289HCID 58455289、化合物

生成物 1

HCID 584552561,3-Dihydroxypropan-2-yl phenyl succinate

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

Phenyl 2-phenyl-1,3-dioxan-5-yl succinate (0.11 g, 0.3 mmol) was dissolved in ethanol (20 ml) under argon and Pd/C (0.09 g, 0.1 mmol) was added. The flask was flushed with hydrogen and allowed to stir under 1 atm H2 at room temperature for 16 h. The crude reaction mixture was passed through a plug of celite and the solvent was removed under reduced pressure yielding (0.9 g, 0.26 mmol, 89%). The product was used without any further purification.

後処理

  1. customThe flask was flushed with hydrogen
  2. customThe crude reaction mixture
  3. customthe solvent was removed under reduced pressure
  4. customyielding (0.9 g, 0.26 mmol, 89%)
  5. customThe product was used without any further purification

出典と根拠

ORDレコード
ord-3c4db04d025a4a348b07f1c720ab1e55
出典データセット
uspto-grants-2013_09
特許番号
US08535655B2

反応ノート

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