Triphenylphosphine → HCID 57976185、化合物
反応式
[N:1]([CH2:4][C:5]1([CH3:23])[NH:9][C:8](=[O:10])[N:7]([C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[C:13]([C:18]([F:21])([F:20])[F:19])[CH:12]=2)[C:6]1=[O:22])=[N+]=[N-].C1C=CC(P(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>C1COCC1.O>[NH2:1][CH2:4][C:5]1([CH3:23])[NH:9][C:8](=[O:10])[N:7]([C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[C:13]([C:18]([F:21])([F:20])[F:19])[CH:12]=2)[C:6]1=[O:22]参加物
5
実験手順
5-Azidomethyl-3-(4-chloro-3-trifluoromethyl-phenyl)-5-methyl-imidazolidine-2,4-dione (500 mg, 1.45 mmoL), Ph3P (380 mg, 1.45 mmoL) in THF (5 mL) and water (1 mL) was heated to reflux for 4 hrs. The solid was filtered through a pad of Celite. The Celite was washed with ethyl acetate. The combined filtrate was concentrated to give a colorless oil, which was used without further purification.