Hexane → HCID 57562627、化合物

HRID 421985ノート

反応式

HRID 421985 の反応式
[NH2:1][C:2]1[N:7]=[C:6]([C:8]([O:10][CH3:11])=[O:9])[CH:5]=[C:4]([Br:12])[CH:3]=1.[C:13]([N:21]=[C:22]=[S:23])(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.CCCCCC>O1CCCC1>[C:13]([NH:21][C:22](=[S:23])[NH:1][C:2]1[N:7]=[C:6]([C:8]([O:10][CH3:11])=[O:9])[CH:5]=[C:4]([Br:12])[CH:3]=1)(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

参加物

5

反応物 3

HCID 8058HexaneHCID 68284Benzoyl isothiocyanateHCID 29919299Methyl 6-amino-4-bromopyridine-2-carboxylate

生成物 1

HCID 57562627HCID 57562627、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

2.74 g of methyl 6-amino-4-bromopyridine-2-carboxylate was dissolved in 15 ml of tetrahydrofuran and 1.63 ml of benzoyl isothiocyanate was added thereto, followed by stirring at room temperature for 13 hours. To the reaction mixture was added 40 ml of hexane. The resulting solid was filtered and washed with hexane. The obtained solid was dried in vacuo to give the title compound.

後処理

  1. filtrationThe resulting solid was filtered
  2. washwashed with hexane
  3. customThe obtained solid was dried in vacuo

出典と根拠

ORDレコード
ord-1fa5bce94db74cc3810b06a83160c2dd
出典データセット
uspto-grants-2012_01
特許番号
US08101621B2

反応ノート

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