Hydrazine hydrate (1:1) → 6-Chloro-1,2,3,4-tetrahydrophthalazine-1,4-dione

HRID 42207

反応式

HRID 42207 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=O)[O:8][C:6](=[O:7])[C:5]2=[CH:11][CH:12]=1.O.[NH2:14][NH2:15]>C(O)(=O)C>[Cl:1][C:2]1[CH:3]=[C:4]2[C:5](=[CH:11][CH:12]=1)[C:6](=[O:7])[NH:15][NH:14][C:9]2=[O:8]

参加物

4

反応物 2

HCID 24654Hydrazine hydrate (1:1)HCID 670444-Chlorophthalic anhydride

生成物 1

HCID 107265786-Chloro-1,2,3,4-tetrahydrophthalazine-1,4-dione収率 95%

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒2 回

実験手順

A mixture of 4-chlorophthalic anhydride (1.81 g, 10 mmol) and acetic acid (15 mL) was added to a solution of hydrazine hydrate (0.62 mL, 10 mmol) in acetic acid (2 mL). The resulting mixture was stirred at reflux for 2 h. The precipitate was collected and dried to give the title compound as a white solid (1.82 g, 95%).

後処理

  1. temperatureat reflux for 2 h
  2. customThe precipitate was collected
  3. customdried

出典と根拠

ORDレコード
ord-ceb71bc6a7a748e4a433d2cfcdfb347b
出典データセット
uspto-grants-2013_09
特許番号
US08536168B2

関連ノート

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