Sodium Sulfite → Sodium 5-bromo-2-methoxybenzenesulfinate

HRID 42355ノート

反応式

HRID 42355 の反応式
[O-]S([O-])=O.[Na+:5].[Na+].C([O-])(O)=O.[Na+].[Br:12][C:13]1[CH:14]=[CH:15][C:16]([O:23][CH3:24])=[C:17]([S:19](Cl)(=[O:21])=[O:20])[CH:18]=1>O.O1CCOCC1>[Br:12][C:13]1[CH:14]=[CH:15][C:16]([O:23][CH3:24])=[C:17]([S:19]([O-:21])=[O:20])[CH:18]=1.[Na+:5]

参加物

6

反応物 3

HCID 24437Sodium SulfiteHCID 516892Sodium BicarbonateHCID 5200205-Bromo-2-methoxybenzene-1-sulfonyl chloride

生成物 1

HCID 67162120Sodium 5-bromo-2-methoxybenzenesulfinate

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 312751,4-Dioxane溶媒

反応条件

温度
70 °C

実験手順

To a solution of Na2SO3 (1.42 g) and NaHCO3 (0.948 g) in H2O (17 ml) at 70° C. was added a solution of 5-bromo-2-methoxybenzene-1-sulfonyl chloride (2 g) in dioxane (17 ml) dropwise. The reaction mixture was stirred at 70° C. for 80 minutes and cooled to room temperature. The solvent was removed under vacuum to yield sodium 5-bromo-2-methoxybenzenesulfinate as white solid. The solid was placed under high vacuum overnight and used without further purification.

後処理

  1. temperaturecooled to room temperature
  2. customThe solvent was removed under vacuum

出典と根拠

ORDレコード
ord-af953d32c592450796c85f7988a72c99
出典データセット
uspto-grants-2013_09
特許番号
US08536187B2

反応ノート

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