5-ethyl-6-nitro-2,3-dihydro-1H-indole → 5-ethyl-6-nitro-1H-indole
反応式
[CH2:1]([C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[NH:8][CH2:7][CH2:6]2)[CH3:2]>C(Cl)Cl.O=[Mn]=O>[CH2:1]([C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[NH:8][CH:7]=[CH:6]2)[CH3:2]参加物
4
実験手順
To a solution of 5-ethyl-6-nitro-2,3-dihydro-1H-indole (1.9 g, 9.9 mmol) in CH2Cl2 (30 mL) was added MnO2 (4 g, 46 mmol). The mixture was stirred at room temperature for 8 h. The solid was filtered off and the filtrate was concentrated to dryness to give crude 5-ethyl-6-nitro-1H-indole (1.9 g, quant.).
後処理
- filtrationThe solid was filtered off
- concentrationthe filtrate was concentrated to dryness
出典と根拠
- ORDレコード
- ord-41da9e2492494e2a9e5e092007e20e4c
- 出典データセット
- uspto-grants-2012_01
- 特許番号
- US08101767B2
反応ノート
読み込み中…